AFC South
Houston Texans
12-5
| Week | Opponent | Result |
|---|---|---|
| 1 |  at Los Angeles Rams | L 9-14 |
| 2 |  vs Tampa Bay Buccaneers | L 19-20 |
| 3 |  at Jacksonville Jaguars | L 10-17 |
| 4 |  vs Tennessee Titans | W 26-0 |
| 5 |  at Baltimore Ravens | W 44-10 |
| 7 |  at Seattle Seahawks | L 19-27 |
| 8 |  vs San Francisco 49ers | W 26-15 |
| 9 |  vs Denver Broncos | L 15-18 |
| 10 | vs Jacksonville Jaguars | W 36-29 |
| 11 | at Tennessee Titans | W 16-13 |
| 12 |  vs Buffalo Bills | W 23-19 |
| 13 |  at Indianapolis Colts | W 20-16 |
| 14 |  at Kansas City Chiefs | W 20-10 |
| 15 |  vs Arizona Cardinals | W 40-20 |
| 16 |  vs Las Vegas Raiders | W 23-21 |
| 17 |  at Los Angeles Chargers | W 20-16 |
| 18 | vs Indianapolis Colts | W 38-30 |